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  • br Design of study br Epidemiological and

    2022-09-15


    Design of study
    Epidemiological, and clinical study involved gender, age, res-idency, site of cancer, family history, past history, year of onset, smoking history, staging and histopathology types are observed.
    Statistical analysis
    The significances via different tests to compares between the epidemiological results.
    Results
    Significant result
    Area of study The prevalence, family history, cancer site, year of man-
    There were significant differences among age groups and histopathological patterns (p < 0.001) (Table 1).
    Un-significant results
    They recorded no significant differences among gender, resi-dency, tobacco habits, alcohol consumption and presentation (p > 0.05 and p > 0.01) (Table 1).
    Discussion
    Because of low socioeconomic status, insufficient screening methods, doubtful early detection, low educational level, errors in diagnosis and unavailability of diagnostic tools, the prevalence was 3.75% which less than expected in compari-son with reports from other countries in the world according to WHO, NIC, NICE and CRUK.1,2,4–7 The percent of cancer were higher in developed countries as US, UK, Australia, Ger-many, France, Italy, Spain, Canada, Japan and Turkey, due to increasing of risky factors as sedentary lifestyle, alcohol con-sumption, cigarette smoking, obesity and meaty food.6–9 In developing and poor cities the ratios different.7 The stud-ies showed high prevalence in Jordan, Iran, Egypt and Saudi Arabia but it SC 236 low in African countries.8 The most age groups affected in this study were 40–60 years, as 41–50 and 51–60, in 23.94% and 30.99% respectively. This recorded in the most studies conducted worldwide.1–3,7
    About gender and residency, there were no significant rela-tionship and that belong to the nature of cancer, which not related to sex or living areas. Cigarette smoking and alcohol consumption play risk role, but there were no significant pre-sented or obtained. While in many studies in other countries showed a strong relation between cancer and tobacco habit and alcohol intake.6,7 In America, Europa and Asia, the family history of colorectal cancer, and family history of other can-cer, if positive, the incidence will increase,3,6,7 which is 42.25% in this study. The most common site of carcinoma was left colon, which presented in 61.97% and this due to anatomic circumferential. According to Giovannucci and Wu, the most common site is the sigmoid 25% followed by the rectum 21%, cecum 20%, rectosigmoid junction 20%, transverse colon 15%, ascending colon 10%.6 This explain by many reasons as inaccuracy of investigation methods or neglected accu-rate results of colonoscopy. Because off increase awareness among national people with increased of buildup of oncol-ogy centers in our countries, we obtained slight increase in new cases detection of colorectal carcinoma from 2013 to 2016. The viable symptoms and sings found in different proportions of no significant. On staging, the most common stages were advance as IIIA, IIIB, IIIC and IV in 12.67%, 16.90%, 19.72%, 15.49% respectively. These results were like other studies con-ducted in Asia, Europa and South America.5,7–9 Those due to late diagnosis, un-availability of screening tools and decreased awareness. Another studies in developed countries as US, UK, Australia, Canada, New Zealand, Japan, South Korea and China, determination of excite cancer in early stages due to increase screening facilities, increase awareness about extinction and available of methods of early detection.6–9 The most common histopathological pattern was adenocarcinoma (well, poor, 
    Table 1 – All criteria of colorectal cancer.
    Variables
    n
    Undifferentiated adenocarcinoma