br Ghoussaini M Fletcher O Michailidou
5. Ghoussaini M, Fletcher O, Michailidou K, et al. Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012; 44:312-8. 6. Michailidou K, Beesley J, Lindstrom S, et al. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Nat Genet 2015; 47:373-80.
7. Peng S, Lü B, Ruan W, Zhu Y, Sheng H, Lai M. Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies. Breast Cancer Res Treat 2011; 12:309-24.
12. Sapkota Y, Mackey JR, Lai R, et al. Assessing SNP-SNP interactions among DNA repair, modification and metabolism related pathway genes in breast cancer sus-ceptibility. PLoS One 2013; 8:e64896.
15. Gonzalez-Suarez E, Jacob A, Jones J, et al. RANK ligand mediates progestin induced mammary epithelial proliferation and carcinogenesis. Nature 2010; 468:103-7. 16. Tan W, Zhang W, Strasner A, et al. Tumour infiltrating regulatory T NVP2 stim-ulate mammary cancer metastasis through RANKL-RANK signalling. Nature 2011; 470:548-53.
18. Libreros S, Garcia-Areas R, Iragavarapu-Charyulu V. CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors. Immunol Res 2013; 57:99-105.
20. Lopes N, Paredes J, Costa JL, Ylstra B, Schmitt F. Vitamin D and the mammary gland: a review on its role in normal development and breast cancer. Breast Cancer Res 2012; 14:211.
21. McCullough ML, Stevens VL, Diver WR, et al. Vitamin D pathway gene poly-morphisms, diet, and risk of postmenopausal breast cancer: a nested caseecontrol study. Breast Cancer Res 2007; 9:R9.
23. Omar HS, Shaker OG, Nassar YH, Marzouk SA, ElMarzouky MS. The associa-tion between RANKL and osteoprotegerin gene polymorphisms with breast cancer. Mol Cell Biochem 2015; 403:219-29.
24. Ney JT, Juhasz-Boess I, Gruenhage F, et al. Genetic polymorphism of the OPG gene associated with breast cancer. BMC Cancer 2013; 13:40.
26. Sinotte M, Rousseau F, Ayotte P, et al. Vitamin D receptor polymorphisms (FokI, BsmI) and breast cancer risk: association replication in two caseecontrol studies within French Canadian population. Endocr Relat Cancer 2008; 15:975-83. 27. Tang C, Chen N, Wu M, et al. Fok1 polymorphism of vitamin D receptor gene contributes to breast cancer susceptibility: a meta-analysis. Breast Cancer Res Treat 2009; 117:391-9.
28. Shahabi A, Alipour M, Safiri H, et al. Vitamin D receptor gene polymorphism: association with susceptibility to early-onset breast cancer in Iranian, BRCA1/2-mutation carrier and non-carrier patients. Pathol Oncol Res 2018; 24:601-7.
29. Rashid MU, Muzaffar M, Khan FA, et al. Association between the BsmI poly-morphism in the vitamin D receptor gene and breast cancer risk: results from a Pakistani caseecontrol study. PLoS One 2015; 10:e0141562.
30. Zhao HY, Liu JM, Ning G, et al. The influence of Lys3Asn polymorphism in the osteoprotegerin gene on bone mineral density in Chinese postmenopausal women. Osteoporos Int 2005; 16:1519-24.
31. Arko B, Preelj J, Komel R, Kocijani A, Hudler P, Marc J. Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis. J Clin Endocrinol Metab 2002; 87:4080-4.
34. Arai H, Miyamoto KI, Taketani Y, et al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japan women. J Bone Miner Res 1997; 12:915-21.
36. Luo XY, Yang MH, Wu FX, et al. Vitamin D receptor gene BsmI polymorphism B allele, but not BB genotype, is associated with systemic lupus erythematosus in a Han Chinese population. Lupus 2012; 21:53-9.
37. Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using David Bioinformatics Resources. Nature Protoc 2009; 4:44-57. 38. Solé X, Guinó E, Valls J, Iniesta R, Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006; 22:1928-9.
39. Ella B, Mikko K, Yrjö L, Heikki M. Linkage disequilibrium between chromosomes in the human genome: test statistics and rapid computation. Publication C Report C-2010-5. Helsinki, Finland; Department of Computer Science Series, University of Helsinki.
41. Obr AE, Grimm SL, Bishop KA, Pike JW, Lydon JP, Edwards DP. Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Mol Endocrinol 2013; 27:1808-24.
45. Haussler MR, Haussler CA, Whitfield GK, et al. The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “fountain of youth” to mediate healthful aging. J Steroid Biochem Mol Biol 2010; 12:88-97.