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br AS HJM agreed to be
2020-08-18
• AS, HJM, agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Acknowledgements None. References [6] Gil-Rendo A, Martínez-Regueira F, Zornoza G, García
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br Influence of the ANLR on OS br
2020-08-18
Influence of the ANLR on OS The relationship between the ANLR and clinicopathological data was compared (Table 3). The high ANLR group was dominated by patients with higher ASA scores, larger tumor sizes, and more advanced staging, and patients who were prone to lymphovascular invasion (all P
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br Ghoussaini M Fletcher O Michailidou
2020-08-14
5. Ghoussaini M, Fletcher O, Michailidou K, et al. Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012; 44:312-8. 6. Michailidou K, Beesley J, Lindstrom S, et al. Genome-wide association analysis of more than 120,000 individuals identifies 15 ne
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br TCGA Cohort br METABRIC Cohort br GDPH
2020-08-14
TCGA Cohort METABRIC Cohort GDPH Cohort WT KMT2C MT KMT2C WT KMT2C MT KMT2C WT KMT2C MT KMT2C Premenopausal NA YES Ductal NA Histologic grade I II III NA Positive Positive Positive Positive NA NA AR Positive Negative NA
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br OH br Dororubicin DOX OMe O OH O H
2020-08-12
OH Dororubicin (DOX) OMe O OH O H O OH HN O O O B Arylboronate promoiety O Figure 1. General structure of the arylboronate prodrugs of doxorubicin. Six cancer cell lines originating from different organs (breast cancer MCF-7 and the resistant counterpart MCF-7 MDR,
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Until now analytical techniques for
2020-08-12
Until now, analytical techniques for HE4 were mainly focused on photoelectrochemical sensing method [8], chemiluminescence im-munoassay [9], electrochemical method [10] and molecularly im-printed photoelectrochemical sensing strategy [11]. Nevertheless, these Resolvin E 1 methods were limited in lin
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br Background and Aims According to guidelines endoscopic re
2020-08-12
Background and Aims: According to guidelines, endoscopic resection should only be performed for patients whose early gastric cancer invasion depth is within the mucosa or submucosa of the stomach regardless of Riboflavin phosphate node involvement. The accurate prediction of invasion depth based
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Conflict of interest statement br The authors declared no co
2020-08-12
Conflict of interest statement The authors declared no conflicts of interest. Gandin, V., Khalkar, P., Braude, J., Fernandes, A.P., 2018. Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment. Free Radic. Biol. Med. 127, 80-97. Jose, G.M., Raghavankut
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br Fig A miR expression in prostate cancer tissues and
2020-08-12
Fig. 1. (A) miR-93 expression in prostate cancer tissues and human benign prostatic hyperplasia tissues detected by qRT-PCR; (B) miR-93 expression in prostate cancer tissues and human benign prostatic hyperplasia tissues detected by in situ hybridization; (C) miR-93 expression in prostate cancer A
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br Fig Anticolon cancer e ect of MP PPPD
2020-08-12
Fig. 6. Anticolon cancer effect of MP/PPPD in vitro. A) MTT test; B) cell apoptosis test with FCM. Fig. 7. Anticolon cancer effect of MP/PPPD in subcutaneous tumor model. A) Body weight of different groups. B) Tumor growth curves. C) Tumor weight. D) Tumor photos of GS, PPPD, pVax/PPPD and MP/PPPD
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br Variable Adjuvant Neoadjuvant Chemoradiation Surgery
2020-08-12
Variable Adjuvant Neoadjuvant Chemoradiation Surgery Only P-Valuea Distance from Incisors to Proximal Edge r> Tumor Size b Margin Status Grade Differentiation b T-Stage b N-Stageb AJCC TNM Staging b Adjusted Survival Rates ACCEPTED MANUSCRIPT b Pathologic data, if
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br level of the GFP tagged POI with vemurafenib treatment
2020-08-12
level of the GFP-tagged POI), with vemurafenib treatment compared to the DMSO-treated control (Figure 7C). This indi-cates that MEK1DD overexpression contributes to cell survival. Similarly, all nine examined kinases showed an enrichment of cell abundance in the fourth bin; in six cases, this enri
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br are thought to cause CC
2020-08-12
are thought to cause CC and they express E6, E7, E1 and E2 oncogenes in the early stages and L1, L2 and E4 in late stages. E6 mediates pro-teasome dependent or independent p53 (a tumor suppressor) turnover and inactivates MDM2 while E7 mediates phosphorylated pRb-medi-ated release of E2F that enha
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br To examine whether the mutation
2020-08-12
To examine whether the mutation of SPOP is correlated to aberrant NANOG-mediated gene expression in PCa, we analyzed the gene-expression-based signatures from human clinical specimens with high expression levels of NANOG versus SPOP mutation. By two-class unpaired significance analysis of microarr
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br P compared to corresponding control or
2020-08-07
***P have also demonstrated that restoration of miR-1291 expression/func-tion suppresses the proliferation, migration, invasion, and tumorigen-esis of PC cells through the induction of apoptosis and sybr安全dna凝胶染料 arrest, as well as alteration of PC cell metabolome [17,18]. In addition, miR-1291
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